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Studies of the occupational health problems of firefighters indicate that the principal hazards (aside from asphyxiation) are irritation of the eyes and respiratory tract, polymer fume fever, pulmonary edema, and long-term damage of lungs, heart, and other internal organs.

Firefighters, who are facing fires, are frequently exposed to hazardous materials including CO, hydrogen cyanide, hydrogen chloride, benzene, and sulfur dioxide.

The second group included 50 firefighters from Khobar.

An additional group of 50 male nonfirefighters volunteered from both cities as normal controls, age ranging from 20 to 55 years.

A written informed consent was obtained from all participants.

Two groups of male firefighters volunteered to participate in the study: The first group included 50 firefighters from Dammam.

Peripheral blood smear was made for all participants, using an automated stainer, Wright stain.

Statistical analysis Statistical analysis was performed on a personal computer using Statistical Package for the Social Sciences version 19 (IBM SPSS statistics, 19th edn. Data are presented as arithmetic mean ± standard deviation.

From [Table 2] and [Figure 1], it is evident that mean levels of liver enzymes, AST, ALT, and γ-GT, uric acid, LDL cholesterol (LDL-C), HDL, CK, and lactate dehydrogenase (LDH) were statistically significantly elevated in Dammam firefighters as compared to normal control group, while nonsignificant changes were observed in all other studied parameters as compared to normal control group.

The first group included 50 firefighters from Dammam while the second group included 50 firefighters from Khobar.

An additional control group of 50 male nonfirefighters from both cities was included in the study.

Lipid profile as total cholesterol, triglyceride, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) and cardiac profile as creatine kinase (CK) and lactic dehydrogenase were investigated.

Iron profile by measuring serum iron, total iron-binding capacity, and serum ferritin was observed.

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